… of the human DNA polymerase γ accessory subunit, the … of this accessory subunit on DNA
replication by DNA polymerase γ… accessory subunit as the cause of processive DNA synthesis …

… for DNA—To investigate the cause of the high processivity conferred by the accessory
subunit we performed steady state kinetic analysis of the native HeLa pol …

… catalytic subunit of pol γ is sensitive to N-ethylmaleimide-… the p140•p55 complex display
nearly complete resistance to NEM … -kDa accessory subunit, which confers processivity to the pol …

… out exonucleolytic proofreading and its p55 accessory subunit. … a native heterodimer (Lim
et al., 1999). Reconstitution of p140�… processive DNA synthesis and confers N-ethylmaleimide …

… and overproduced the catalytic subunit of human pol γ in insect … , and the drug resistance
conferred by these mutations are … Cardiac mitochondrial DNA polymerase-gamma is inhibited …

… role of the p55 accessory subunit for highly processive mtDNA … DNA synthesis, and confers
N-ethylmaleimide resistance. … N-ethylmaleimide (NEM) protection assays, no enhancement of …

… poorly able to bind to the p55 accessory subunit, as shown by … suggesting that E1143G does
not confer a purely beneficial effect … of the catalytic subunit by N-ethylmaleimide. The G416A …

… subunit, the accessory subunit confers high processivity to … catalytic (p140) and accessory
(p55) subunits separately, as well … N ‐ethylmaleimide (NEM) inhibition of pol γ where the Hp55 …

… DNA polymerase gamma has three main roles in health and … accessory subunit is a 55 kDa
protein (p55) required for tight DNA binding and processive DNA synthesis (Lim et al., 1999). …

… the p55 accessory subunit is required for enhanced DNA … γ is extremely sensitive to inhibition
by N-ethylmaleimide (NEM… a 2-fold molar excess of p55 conferred resistance to NEM, most …