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NOB1

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NOB1

Identifiers

NOB1, ART-4, MST158, NOB1P, PSMD8BP1, MSTP158, NIN1/PSMD8 binding protein 1 homolog, NIN1 (RPN12) binding protein 1 homolog

External IDs

OMIM: 613586; MGI: 1914869; HomoloGene: 31924; GeneCards: NOB1; OMA:NOB1 - orthologs

Gene location (Human)

Chr.	Chromosome 16 (human)^[1]

Band	16q22.1	Start	69,741,871 bp^[1]
Band	16q22.1	End	69,754,926 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 8 (mouse)^[2]

Band	8\|8 D3	Start	108,139,118 bp^[2]
Band	8\|8 D3	End	108,151,683 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

body of pancreas

right adrenal gland

right adrenal cortex

left adrenal gland

left adrenal cortex

left ovary

stromal cell of endometrium

uterine tube

right ovary

mucosa of esophagus

Top expressed in

hand

epiblast

morula

embryo

embryo

primitive streak

otolith organ

utricle

ventricular zone

foot

More reference expression data

n/a

Gene ontology
Molecular function	metal ion binding endoribonuclease activity
Cellular component	preribosome, small subunit precursor nucleus cytosol nucleoplasm
Biological process	maturation of SSU-rRNA visual perception RNA phosphodiester bond hydrolysis, endonucleolytic rRNA processing cleavage involved in rRNA processing ribosomal small subunit biogenesis
Sources:Amigo / QuickGO

Species

Human

Mouse


28987


67619


ENSG00000141101


ENSMUSG00000003848


Q9ULX3


Q8BW10

RefSeq (mRNA)


NM_014062


NM_026277

RefSeq (protein)


NP_054781


NP_080553

Location (UCSC)

Chr 16: 69.74 – 69.75 Mb

Chr 8: 108.14 – 108.15 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

RNA-binding protein NOB1 is a protein that in humans is encoded by the NOB1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141101 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003848 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang Y, Ni J, Zhou G, Yuan J, Ren W, Shan Y, Tang W, Yu L, Zhao S (Sep 2005). "Cloning, expression and characterization of the human NOB1 gene". Mol Biol Rep. 32 (3): 185–9. doi:10.1007/s11033-005-3141-7. PMID 16172919. S2CID 12892523.
^ "Entrez Gene: NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)".

Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Fatica A, Oeffinger M, Dlakić M, Tollervey D (2003). "Nob1p is required for cleavage of the 3' end of 18S rRNA". Mol. Cell. Biol. 23 (5): 1798–807. doi:10.1128/MCB.23.5.1798-1807.2003. PMC 151717. PMID 12588997.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Daniele A, Altruda F, Ferrone M, et al. (1992). "Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli". Mol. Cell. Biochem. 107 (2): 87–94. doi:10.1007/bf00225511. PMID 1791827. S2CID 25617287.

v t e PDB gallery
2con: Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA

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