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Arthur Beck Pardee (Chicago, 13 de julho de 1921 - 24 de fevereiro de 2019) foi um farmacologista e bioquímico estadunidense. Recebeu em 1960 o Prêmio Pfizer de Química de Enzimas. Morreu 24 de fevereiro de 2019 aos 97 anos de idade. Arthur Beck Pardee (* 13. Juli 1921 in Chicago, Illinois; † 24. Februar 2019) war ein US-amerikanischer Pharmakologe und Biochemiker, der 1975 den renommierten Rosenstiel Award erhielt. Arthur Beck Pardee (July 13, 1921 – February 24, 2019) was an American biochemist. One biographical portrait begins "Among the titans of science, Arthur Pardee is especially intriguing." There is hardly a field of molecular biology that is not affected by his work, which has advanced our understanding through theoretical predictions followed by insightful experiments. He is perhaps most famous for his part in the 'PaJaMo experiment' of the late 1950s, which greatly helped in the discovery of messenger RNA. He is also well known as the discoverer of the restriction point, in which a cell commits itself to certain cell cycle events during the G1 cycle. He did a great deal of work on tumor growth and regulation, with a particular focus on the role of estrogen in hormone-responsive tumors. He
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Arthur Beck Pardee (Chicago, 13 de julho de 1921 - 24 de fevereiro de 2019) foi um farmacologista e bioquímico estadunidense. Recebeu em 1960 o Prêmio Pfizer de Química de Enzimas. Morreu 24 de fevereiro de 2019 aos 97 anos de idade. Arthur Beck Pardee (* 13. Juli 1921 in Chicago, Illinois; † 24. Februar 2019) war ein US-amerikanischer Pharmakologe und Biochemiker, der 1975 den renommierten Rosenstiel Award erhielt. Arthur Beck Pardee (July 13, 1921 – February 24, 2019) was an American biochemist. One biographical portrait begins "Among the titans of science, Arthur Pardee is especially intriguing." There is hardly a field of molecular biology that is not affected by his work, which has advanced our understanding through theoretical predictions followed by insightful experiments. He is perhaps most famous for his part in the 'PaJaMo experiment' of the late 1950s, which greatly helped in the discovery of messenger RNA. He is also well known as the discoverer of the restriction point, in which a cell commits itself to certain cell cycle events during the G1 cycle. He did a great deal of work on tumor growth and regulation, with a particular focus on the role of estrogen in hormone-responsive tumors. He is also well known for the development of various biochemical research techniques, most notably the differential display methodology, which is used in examining the activation of genes in cells. More recently he championed the acceptance and adoption of the conceptual review as a valuable approach to unearthing new knowledge from the enormous stores of information in the scientific literature. He died in February 2019 at the age of 97.
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